|Scott S. Reuben|
|Criminal charge||Health care fraud|
|Criminal penalty||Six months in federal prison, three years' supervised release, $5,000 fine, forfeiture of $50,000, $360,000 restitution|
|Criminal status||Released in 2010|
|Conviction(s)||Pleaded guilty February 24, 2010|
Scott S. Reuben (born 1958) is an American anesthesiologist who was Professor of Anesthesiology and Pain Medicine at Tufts University in Boston, Massachusetts and chief of acute pain at Baystate Medical Center in Springfield, Massachusetts before being sentenced to prison for healthcare fraud. Reuben was considered a prolific and influential researcher in pain management, and his purported findings altered the way millions of patients are treated for pain during and after orthopedic surgeries. Reuben has now admitted that he never conducted any of the clinical trials on which his conclusions were based "in what may be considered the longest-running and widest-ranging cases of academic fraud." Scientific American has called Reuben the medical equivalent of Bernie Madoff, the former NASDAQ chairman who was convicted of orchestrating a $65-billion Ponzi scheme.
Reuben was educated at Columbia University. He graduated from medical school at the State University of New York at Buffalo in 1985 and undertook his anesthesiology residency at Mount Sinai Medical Center in New York.
Reuben fell under suspicion when Baystate conducted a routine audit in May 2008 which revealed that Reuben hadn't been given approval for two studies he had intended to present during the hospital's research week. On March 10, 2009 a Baystate spokeswoman announced that Reuben admitted to fabricating many of the data underlying his research. Reuben never conducted the clinical trials that he wrote about in 21 journal articles dating from at least 1996. In some cases, he even invented the patients. Although Reuben often co-wrote papers with other researchers, Baystate found that the other researchers did not know about or participate in Reuben's studies, and their names were forged on documents. The hospital asked the journals to retract the studies, which reported favorable results from painkillers including Pfizer Inc.'s Bextra, Celebrex and Lyrica and Merck & Co. Inc.'s Vioxx. His studies also claimed Wyeth's antidepressant Effexor could be used as a painkiller. Pfizer gave Reuben five research grants between 2002 and 2007. He was a paid member of the company's speakers bureau, giving talks about Pfizer drugs to colleagues. Reuben also wrote to the Food and Drug Administration, urging the agency not to restrict the use of many of the painkillers he studied, citing his own data on their safety and effectiveness.
"Doctors have been using (his) findings very widely," said Dr. Steven Shafer, editor of Anesthesia and Analgesia, a scientific journal that published ten articles identified as containing fraudulent data.  "His findings had a huge impact on the field." He also described Reuben's actions as the biggest case of fraud in the history of anesthesiology. Paul White, another editor at the journal, estimates that Reuben's studies led to the sale of billions of dollars' worth of drugs which may have actually slowed down recovery times for patients.
Reuben's work had actually come under scrutiny as early as 2007, when several anesthesiologists noticed his studies never showed negative results. Greg Koski, former director of the Office for Human Research Protections, said the fraud was unusual because Reuben was able to carry it on for almost 13 years without being caught by the peer review process.
All of Reuben's 21 fraudulent articles, as well as the article abstracts, are documented in Healthcare Ledger Magazine.
On January 7, 2010; Reuben agreed to plead guilty to one count of health care fraud. Prosecutors alleged that Reuben obtained thousands of dollars in grants for research that he never performed. He formally pleaded guilty on February 21, 2010 before Judge Michael Ponsor. On May 24, Ponsor sentenced him to six months in prison, followed by three years of supervised release. He was ordered to pay a $5,000 fine, forfeit $50,000 to the government and make $360,000 in restitution to pharmaceutical companies. The plea deal effectively ended his career as a doctor; most states will not grant medical licenses to convicted felons.
- A Medical Madoff: Anesthesiologist Faked Data in 21 Studies, Scientific American, March 10, 2009
- Doctor Admits Pain Studies Were Frauds, Hospital Says, The New York Times, March 11, 2009
- Fraud Case Rocks Anesthesiology Community, Anesthesiology News, March 2009
- Doctor accused of faking studies; His work dealt with pain drugs, Boston Globe, March 11, 2009
- Mass. doctor accused of fabricating pain studies, Associated Press, March 11, 2009
- Top Pain Scientist Fabricated Data in Studies, Hospital Says, Wall Street Journal, March 11, 2009
- "Retraction Notice", Steven L. Shafer, Anesthesia and Analgesia, 20 February 2009
- Dr. Scott Reuben, former chief of acute pain at Baystate Medical Center in Springfield, pleads guilty to health-care fraud. The Republican, January 15, 2010
- Scott Reuben, a former Baystate doctor who faked research, sentenced to 6 months for health care fraud, The Republican, June 24, 2010
- Anesthesiologist sentenced on health care fraud charge. United States Attorney for the District of Massachusetts, June 24, 2010
- Scott S. Reuben: Debarment Order (FDA)