Born Scrope Bernard in Pestel Amberg in New Jersey, he was the sixth and youngest son of Sir Francis Bernard, 1st Baronet and Amelia Offley, daughter of Stephen Offley. In 1818, he succeeded his older brother Thomas as baronet. Bernard-Morland was educated at Harrow School and Christ Church, Oxford. He graduated with a Bachelor of Arts in 1779 and a Master of Arts two years later. In 1788, he was awarded a Doctor of Civil Laws (DCL). One year later, Bernard-Morland became a member of the College of Laws in London, and in 1795, he was promoted Judge of the Episcopal Court of Durham. In 1811, by Royal Licence, he assumed the surname Bernard-Morland to inherit the estates of his father-in-law.
In 1782, Bernard-Morland was appointed Private Secretary to the Lord Lieutenant of Ireland, an office he held until 1787. He was Secretary to the Commission of Enquiry into Public Offices in 1785 and Gentleman Usher of the Black Rod in Ireland in 1787. Between 1789 and 1792, he was Under-Secretary of State for the Home Department. Bernard-Morland entered the British House of Commons for Aylesbury in 1789. He represented the constituency first in the Parliament of Great Britain then in the Parliament of the United Kingdom until 1806. Subsequently he sat as Member of Parliament for St Mawes until 1808 and again from 1809 to his death in 1830.
On 26 July 1785, he married Harriett Morland, only daughter of William Morland, at St George's, Hanover Square, in London. They had seven children, five sons and two daughters. Bernard-Morland died at his home in Pall Mall, London, aged 71 and was buried in Great Kimble in Buckinghamshire, where he owned an extensive estate. He was succeeded in the baronetcy successively by his third son Francis and then his fourth son Thomas.
- "Leigh Rayment - Baronetage". Retrieved 28 April 2009.
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- Debrett, John (1824). Debrett's Baronetage of England. vol. I (5th ed.). London: G. Woodfall. pp. 501–502.
- Sylvanus, Urban (1830). The Gentleman's Magazine. London: John Harris. pp. 465–466.
- The London Gazette: . 19 February 1811. Retrieved 28 April 2009.
- Haydn, Joseph (1851). The Book of Dignities: Containing Rolls of the Official Personal of the British Empire. London: Longman, Brown, Green and Longman's. p. 175.
- "Leigh Rayment - British House of Commons, Aylesbury". Retrieved 28 April 2009.
- "Leigh Rayment - British House of Commons, St Mawes". Retrieved 28 April 2009.
- Victoria History of the County of Buckingham, vol.2 pp.302 & 304
- Hansard 1803–2005: contributions in Parliament by Sir Scrope Bernard-Morland, 4th Baronet