According to Tyler, the song was inspired by the Massachusetts landscape in wintertime. The song's lyrics also discuss a relationship. It is one of Tyler's favorite Aerosmith songs. The song is highlighted by acoustic guitars, slow haunting vocals, and a strong rhythm. On the Get Your Wings album, the song starts off with a crowd of people cheering, which gradually fades to the howling wind and an acoustic guitar played by Tyler which start off the song. This is done to achieve a blending effect between this song and the previous track, "Train Kept A-Rollin'".
Additionally, the song has been resurrected as a live staple among Aerosmith shows in the 2000s, after not being played much on tours in the late 1980s and 1990s. However, the song was performed at the band's MTV Unplugged performance in 1990. On the Just Push Play Tour in 2001, Tyler and Joe Perry would start off the song at the top of a dual staircase. On the Route of All Evil Tour (2006) and World Tour (2007), Tyler and Joe Perry would start off the song sitting down on chairs at the end of the catwalk.
The song has been covered by Die Kreuzen on the album Gone Away, Tesla on the Reel to Reel 2 album and by Vitamin String Quartet on their Aerosmith tribute album. Boston pianist Yoko Miwa has recorded an instrumental jazz version with her trio, and Seattle's defunct Mother Love Bone (Pearl Jam's precursor) also recorded their version, which is available on scattered bootlegs. It can be found on YouTube as well.
^Davis, Stephen (2003-02-18). Walk This Way: The Autobiography of Aerosmith (Reprint Edition ed.). It Books. p. 214. ISBN9780060515805. ""Seasons of Wither" was about the winter landscape near this house I was living in with Joey near an old chicken farm (in Needham, Mass)."