Serinolamide A

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Serinolamide A
SerinolamideA structure.png
Systematic (IUPAC) name
(R,E)-N-(1-hydroxy-3-methoxypropan-2-yl)-N-methyloctadec-4-enamide
Clinical data
Legal status ?
Identifiers
CAS number  N
ATC code ?
PubChem CID 56597771
ChemSpider 27025743
Chemical data
Formula C23H45NO3 
Mol. mass 383.61 g/mol

Serinolamide A is a naturally occurring eicosanoid derivative related to anandamide, which has been isolated from the marine cyanobacteria Lyngbya majuscula and related species in the Oscillatoria family. Testing established that serinolamide A is an active cannabinoid agonist with moderate potency, having a Ki of 1300nM at CB1 and 5x selectivity over the related CB2 receptor.[1]

See also[edit]

References[edit]

  1. ^ Gutiérrez, M.; Pereira, A. R.; Debonsi, H. M.; Ligresti, A.; Di Marzo, V.; Gerwick, W. H. (2011). "Cannabinomimetic Lipid from a Marine Cyanobacterium". Journal of Natural Products 74 (10): 2313–2317. doi:10.1021/np200610t. PMC 3325759. PMID 21999614.  edit