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Systematic (IUPAC) name
Clinical data
Trade names Geref
AHFS/ Micromedex Detailed Consumer Information
  • US: C (Risk not ruled out)
  • US: Discontinued
86168-78-7 YesY
H01AC04 V04CD03
PubChem CID 16132413
DrugBank DB00010 N
ChemSpider 17289071 N
UNII 89243S03TE N
KEGG D08509 YesY
Synonyms GRF 1–29
Chemical data
Formula C149H246N44O42S
3357.882 g/mol
 N (what is this?)  (verify)

Sermorelin (trade name is Geref) is a growth hormone releasing hormone (GHRH) analogue. It is a 29-amino acid polypeptide representing the 1–29 fragment from endogenous human growth hormone releasing hormone, and is thought to be the shortest fully functional fragment of GHRH.[1] It is used as a test for growth hormone secretion.[2] It is also used as doping substance in sports due to its correlation with increased growth of muscular and skeletal tissue.[3] Sermorelin use is also hypothesized to improve deep rapid eye movement sleep.[3][citation needed]

See also[edit]


  1. ^ Prakash A, Goa KL (August 1999). "Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency". BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy 12 (2): 139–57. doi:10.2165/00063030-199912020-00007. PMID 18031173. 
  2. ^ Pharmacology (Rang, Dale, Ritter & Moore, ISBN 0-443-07145-4, 5th ed., Churchill Livingstone 2003).
  3. ^ a b "Sermorelin Research". Strong Peptides. Retrieved 21 April 2015.