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A seroma is a pocket of clear serous fluid that sometimes develops in the body after surgery. When small blood vessels are ruptured, blood plasma can seep out; inflammation caused by dying injured cells also contributes to the fluid.
Seromas can also sometimes be caused by injury, such as when the initial swelling from a blow or fall does not fully subside. The remaining serous fluid causes a seroma that the body usually gradually absorbs over time (often taking many days or weeks); however, a knot of calcified tissue sometimes remains.
Seromas or lymphatic leaks (lymphoceles) may be difficult to manage at times. Depending on the volume and duration of leakage, control of a leak may take up to a few weeks to resolve with aspiration of serums and the application of pressure dressings. Manual Lymphatic Drainage (MLD) conducted by a trained professional can also assist in managing and treating seromas.
If a serum or leak does not resolve, for example after a soft tissue biopsy, it may be necessary to take the patient back to the operating room in order to place some form of closed suction drain into the wound. This usually is not necessary and conservative management prevails.
- Wong, Elaine K.; Truong, Pauline T.; Kader, Hosam A.; Nichol, Alan M.; Salter, Lee; Petersen, Ross; Wai, Elaine S.; Weir, Lorna; Olivotto, Ivo A. (1 October 2006), "Consistency in seroma contouring for partial breast radiotherapy: Impact of guidelines", Int J Radiat Oncol Biol Phys 66 (2): 372–6, doi:10.1016/j.ijrobp.2006.05.066, PMID 16965989
- Schwartz's principles of surgery: self assessment and board review, 8th edition, chapter 11, patient safety, errors, and complications in surgery
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