Van Neerden also won several U.S. national titles in his career. At the 1994 U.S. Nationals he tied the American Record in the 100m breaststroke, with a time of 1:01.40. This record would stand for two years. Considered one of the world's top breastrokers of the 1990s, Van Neerden finished in the top 20 world rankings for the 100 breaststroke every year from 1990-1996. He consistently ranked as one of the world's fastest 200 breaststrokers throughout these years as well. World-famous swimming coach Jack Nelson, who trained Van Neerden in the early and mid 1990s stated, "Seth Van Neerden is America's finest breaststroker."