Sex and drugs
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Many drugs, both legal and illegal, have side effects which impact on the user's sexual functions. For example, the side effect of many legal antidepressants and antipsychotic drugs is the reduction of sexual desire.
Perhaps the most common drug used is alcohol. At low concentrations of blood alcohol, social inhibitions are reduced, though in higher concentrations it can also inhibit performance. Many other drugs also inhibit sexual performance.
Because drug and alcohol use is commonly presented as an excuse for unacceptable behaviour, it is necessary to treat the idea of a direct causal relation between drug use and unsafe sex with caution. Drugs may provide a socially acceptable excuse for engaging in sexual behaviours in which people may want to engage but perhaps know that they should not.
Since the partial cause of the refractory period is the inhibition of dopamine by an orgasm-induced secretion of prolactin, such potent dopamine receptor agonists as cabergoline may help achieve multiple orgasms as well as the retention of sexual arousal for longer periods. In theory, it can also help to preserve erection after orgasm.
A few drugs can actually increase sexual performance when used to treat erectile dysfunction. These include sildenafil (marketed as Viagra) and tadalafil. Bremelanotide appears to affect sexual desire directly, making it the first scientifically recognized aphrodisiac. This is also true of Melanotan II, upon which bremelanotide is based. Additionally, the alkyl nitrites (poppers) have a long history of use as a sexual enhancement aid, going back about fifty years. According to the text "ISOBUTYL NITRITE and Related Compounds", many researchers agree that the alkyl nitrites may be a true aphrodisiac in the sense of promoting and enhancing sexual response.
- Methamphetamine and sex
- Party and play
- Nitrite inhalants ("Poppers") are sometimes used as an adjunct to sex acts
- Drugs and prostitution
- Wine, women and song
- Post-SSRI sexual dysfunction
- Race K (2009): Pleasure Consuming Medicine: The queer politics of drugs Durham: Duke University Press.
- "The Tobacco Reference Guide". Retrieved 2006-07-15.
- Haake, P.; Exton, M.S.; Haverkamp, J.; Krämer, M.; Leygraf, N.; Hartmann, U.; Schedlowski, M.; Krueger, T.H.C. (April 2002), "Absence of orgasm-induced prolactin secretion in a healthy multi-orgasmic male subject", International Journal of Impotence Research 14 (2): 133–135, doi:10.1038/sj/ijir/3900823, retrieved 2007-07-30
- Krüger TH, Haake P, Haverkamp J, et al. (December 2003). "Effects of acute prolactin manipulation on sexual drive and function in males". Journal of Endocrinology 179 (3): 357–65. doi:10.1677/joe.0.1790357. PMID 14656205.
- "ISOBUTYL NITRITE and Related Compounds". Retrieved 2009-07-29.
- "ALL ABOUT POPPERS". Retrieved 2006-07-15.
- "Sex Under the Influence" on antidepressants, alcohol, marijuana, and ecstasy from the University of California at Santa Barbara
- Marijuana and Sex: A Classic Combination