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Sex determination may refer to:
Development of an organism's sex
- A sex-determination system, a biological system that directs the development of sexual characteristics in an organism
- Sex determination and differentiation (human)
- Sexual differentiation, the development of sexual characteristics in humans
Discernment of an organism's sex
- Prenatal sex discernment, prenatal testing for the discernment of the fetal sex in humans
- Sex assignment, a human social act carrying the assumption that the assigned person will then have a corresponding gender identity
- Sexing, used by biologists and agricultural workers to discern the sex of livestock or other animals
- Gender, including biological sex
- Sexual dimorphism, a phenotypic difference between males and females of the same species, used in sex discernment
- Sex differences in humans
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