Sexual arousal disorder
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Sexual arousal disorder is characterized by a lack or absence of sexual fantasies and desire for sexual activity in a situation that would normally produce sexual arousal, or the inability to attain or maintain typical responses to sexual arousal. The disorder is found in the DSM-IV. The condition should not be confused with a sexual desire disorder.
Signs and symptoms
In women, the symptoms of the disorder include:
- Lack of vaginal lubrication
- Lack of vaginal dilation or lengthening
- Decreased genital tumescence or swelling
- Decreased genital or nipple sensation
However, whether lack of physiological arousal is a reliable symptom of the disorder is questionable. Research has shown that women with arousal deficits and women without arousal deficits show equivalent increases in physiological response during experience of erotic stimuli.
Contrary to popular belief, the disorder is not always caused from a lack of sexual arousal. Possible causes of the disorder include psychological and emotional factors, such as depression, anger, and stress; relationship factors, such as conflict or lack of trust; medical factors, such as depleted hormones, reduced regional blood flow, and nerve damage; and drug use. The lack of sexual arousal may be due to a general lack of sexual desire or due to a lack of sexual desire for the current partner (i.e., situational). A person may always have had no or low sexual desire or the lack of desire may have been acquired during the person's life.
A psychologist will first consider any psychological or emotional problems; while a sex therapist will examine relationship issues; after which a medical doctor will investigate medical causes for the disorder.
Bremelanotide (formerly PT-141) is being studied in clinical tests to increase sexual desire in women. Preliminary results have proven its efficacy. However, development was temporarily suspended due to a side effect of increased blood pressure observed in a small number of subjects who administered the drug intra-nasally. In 2009, Palatin, the company developing the drug, announced positive results without heightened blood pressure effects after a phase I study using a new subcutaneous method of administration.
- DSM-IV, American Psychiatric Association 1994
- Morokoff PJ, Heiman JR (1980). "Effects of Erotic Stimuli on Sexually Functional and Dysfunctional Women". Behaviour Research and Therapy 18 (2): 127–137. doi:10.1016/0005-7967(80)90107-2.
- Laan E, van Driel EM, van Lunsen RHW (June 2008). "Genital Responsiveness in Healthy Women With and Without Sexual Arousal Disorder". Journal of Sexual Medicine 5 (6): 1424–1435. doi:10.1111/j.1743-6109.2008.00827.x.
- "PALATIN TECHNOLOGIES, INC. REPORTS POSITIVE BREMELANOTIDE STUDY; IMPROVED SAFETY PROFILE WITH SUBCUTANEOUS ADMINISTRATION". Retrieved 2009-08-12.