Shigella sonnei

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Shigella sonnei
Scientific classification
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gamma Proteobacteria
Order: Enterobacteriales
Family: Enterobacteriaceae
Genus: Shigella
Species: S. sonnei
Binomial name
Shigella sonnei

Shigella sonnei is a species of Shigella.[1] Together with Shigella flexneri, it is responsible for 90% of shigellosis.[2] Shigella sonnei is named for the Danish bacteriologist Carl Olaf Sonne.[3][4]

Pathophysiology[edit]

Polymerizes host cell actin.

Evolution[edit]

This species is clonal and has spread worldwide. Analysis of 132 strains has shown that they originated from a common ancestor in Europe ~1500 AD.[5]

Treatment[edit]

Antibiotic resistance has been reported.[6]

Growth In Lab[edit]

Can be grown on MAC agar and TSA. Will grow at 37°C optimally, but also grows at 25°C. Facultatively anaerobic as well as chemoorganotrophic. Produces acid when carbohydrates are catabolized.

References[edit]

  1. ^ Shigella sonnei at the US National Library of Medicine Medical Subject Headings (MeSH)
  2. ^ "Shigellosis: Causes". eMedicine. Retrieved February 14, 2012. 
  3. ^ Carl Olaf Sonne at Who Named It?
  4. ^ Shigella sonnei at Who Named It?
  5. ^ Holt, Kathryn E; Baker, Stephen; Weill, François-Xavier; Holmes, Edward C; Kitchen, Andrew; Yu, Jun; Sangal, Vartul; Brown, Derek J; Coia, John E; Kim, Dong Wook; Choi, Seon Young; Kim, Su Hee; da Silveira, Wanderley D; Pickard, Derek J; Farrar, Jeremy J; Parkhill, Julian; Dougan, Gordon; Thomson, Nicholas R (August 2012). "Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe". Nature Genetics 44 (9): 1056–9. doi:10.1038/ng.2369. PMC 3442231. PMID 22863732. Retrieved August 9, 2012. 
  6. ^ Jain SK, Gupta A, Glanz B, Dick J, Siberry GK (June 2005). "Antimicrobial-resistant Shigella sonnei: limited antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility". Pediatric Infectious Disease Journal 24 (6): 494–497. PMID 15933557. 

External links[edit]