"Signs" was covered and recorded live by Tesla for their Five Man Acoustical Jam album in 1990, peaking at number 8 on the Pop charts. This cover had some minor changes to the lyrics: the line "blockin' out the scenery" was changed to "fuckin' up the scenery," and "made up my own little sign" was changed to "made up my own fuckin' sign". A studio version recorded in 2007 used the original lyrics.
ApologetiX recorded a parody of the song titled "Lions", telling the story of Daniel in the lion's den. It was originally included on the cassette of Radical History Tour, and was later re-issued on the "Director's Cut" edition of Isn't Wasn't Ain't.