The S-41 had a parasol wing configuration, with two radial engines mounted on struts between the fuselage and the wing. The cabin was completely enclosed within the all-metal hull and could seat 15 passengers.
The United States Navy purchased three examples and designated them RS-1; these were joined by two Pan Am aircraft pressed into Navy service and designated RS-5.
On 27 August 1931, one of these vessels crash landed at sea while making the run between Halifax N.S. and Boston MA. After two hours clinging to the sides of a partially inflated life raft in rough seas, the 12 survivors were rescued by the F/V Nova Julia, a mackerel seiner out of Gloucester MA, captained by Capt. Leo Favaloro. There was one fatality. Seventy year old Edward Bamwell was assumed trapped in the wreckage as it disappeared beneath the waves just a moment after he gallantly allowed one of the three women passengers to precede him to the waiting raft. The Sikorsky had only been in service one month. Heavy fog was cited as the cause of the crash.