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In genetics a silencer is a DNA sequence capable of binding transcription regulation factors termed repressors. Upon binding, RNA polymerase is prevented from initiating transcription thus decreasing or fully suppressing RNA synthesis.
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| Transcriptional regulation |
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prokaryotic
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eukaryotic
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both
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| Promotion |
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Initiation (prokaryotic,
eukaryotic) |
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| Elongation |
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Termination
(prokaryotic,
eukaryotic) |
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see also disorders of transcription and post transcriptional modification
B bsyn: dna (repl, cycl, reco, repr) · tscr (fact, tcrg, nucl, rnat, rept, ptts) · tltn (risu, pttl, nexn) · dnab, rnab/runp · stru (domn, 1°, 2°, 3°, 4°)
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