Simion Stanciu was born in Bucharest, Romania, into a musical family. His father was a cellist, and his brothers were also instrumentalists. He registered at the Bucharest conservatory, initially studying the violin, but from 14 years of age onwards, he increasingly concentrated on playing the pan pipes. Due to his education in classical music, he was able to make a new repertory accessible for this instrument, which hitherto was only significant in the folk music traditions of various countries and in popular music. He chose his stage name, which not only signifies the nymphSyrinx in ancient Greek mythology, but also the Pan flute itself.
The range of Stanciu's repertoire included Baroque and Classical instrumental concerts (Vivaldi, Bach, Mozart etc.) adapted for the Pan flute, collaborations with Rock music artists like The Moody Blues or Yes, as well as recordings in the fields of Jazz and light music. He also performed the soundtrack recording for the film Quest for Fire.
Stanciu founded the Pan flute school Akademie Syrinx. He died aged 60 in Geneva, Switzerland, after a protracted illness.