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Shepherd was born in Bristol, England. He went to school at Clifton College in Bristol and was a contemporary of the director Roger Michell in Brown's House. He subsequently attended Manchester Metropolitan University and Bristol Old Vic Theatre School and was a member of the National Youth Theatre.
As well as his television appearances he has had many notable stage and film roles since 1980.
In popular culture
Simon Shepherd was regularly mentioned in the BBC Comedy Gimme Gimme Gimme as Tom's crush and appeared as himself in an episode of each series.
On 16 February 2011 Simon Shepherd guest-starred in the 200th episode of the BBC TV Drama Doctors. The featured story was about a deadly virus that was unleashed at The Mill in which virologist George Liston (Simon Shepherd) was responsible for the outbreak. He is to play the role of Sir Norman Cavendish in the new play The Duck House by Dan Patterson and Colin Swash. Starring alongside Ben Miller and Diana Vickers, the show is a political satire based on the UK parliamentary expenses scandal and will embark on a 5 week tour in October 2013 before transferring to London's Vaudeville Theatre.
He married the costume designer Alexandra Byrne in 1980 and they have four children. Shepherd supports several charities, especially those involving the well-being of children (Barnardo's, Tearfund BOPS and Save the Children).
- "The Duck House: MPs' expenses satire heads for West End". bbc.co.uk/news. BBC News. 16 September 2013. Retrieved 16 September 2013.
- "Political Comedy The Duck House Will Play London's Vaudeville; Cast Announced". playbill.com. Playbill. 16 September 2013. Retrieved 20 September 2013.