Sodium aurothiomalate
| Sodium aurothiomalate | |
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Sodium aurothiomalate |
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Sodium 2-(auriosulfanyl)-3-carboxypropanoate |
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| Identifiers | |
| CAS number | 12244-57-4 |
| PubChem | 16760302 |
| ChemSpider | 7827788 |
| ChEBI | CHEBI:35863 |
| ATC code | M01 |
| Gmelin Reference | 1211734 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C4H4AuNaO4S |
| Molar mass | 368.09 g mol−1 |
| Pharmacology | |
| Bioavailability | 0% |
| Routes of administration |
Intramascular injection |
| Legal status |
POM(UK) |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Sodium aurothiomalate (gold sodium thiomalate) is a gold compound that is used for its antirheumatic effects to treat rheumatoid arthritis.[1][2] In the United Kingdom only the intramuscular injection drug Myocrisin (which contains a mixture of sodium aurothiomalate and disodium aurothiomalate) and the orally taken auranofin are used medically.
References [edit]
- ^ Jessop, J. D.; O'Sullivan, M. M.; Lewis, P. A.; Williams, L. A.; Camilleri, J. P.; Plant, M. J.; Coles, E. C. (1998). "A long-term five-year randomized controlled trial of hydroxychloroquine, sodium aurothiomalate, auranofin and penicillamine in the treatment of patients with rheumatoid arthritis". British journal of rheumatology 37 (9): 992–1002. doi:10.1093/rheumatology/37.9.992. PMID 9783766.
- ^ Iqbal, M. S.; Saeed, M.; Taqi, S. G. (2008). "Erythrocyte Membrane Gold Levels After Treatment with Auranofin and Sodium Aurothiomalate". Biological Trace Element Research 126 (1–3): 56–64. doi:10.1007/s12011-008-8184-x. PMID 18649049.
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