Sodium aurothiomalate

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Sodium aurothiomalate
Identifiers
CAS number 12244-57-4 YesY
PubChem 16760302
ChemSpider 7827788 YesY
ChEBI CHEBI:35863 YesY
ATC code M01CB01
Gmelin Reference 1211734
Jmol-3D images Image 1
Properties
Molecular formula C4H4AuNaO4S
Molar mass 368.09 g mol−1
Pharmacology
Bioavailability 0%
Routes of
administration
Intramascular injection
Legal status

POM(UK)

 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Sodium aurothiomalate (gold sodium thiomalate) is a gold compound that is used for its antirheumatic effects to treat rheumatoid arthritis.[1][2] In the United Kingdom only the intramuscular injection drug Myocrisin (which contains a mixture of sodium aurothiomalate and disodium aurothiomalate) and the orally taken auranofin are used medically.

References [edit]

  1. ^ Jessop, J. D.; O'Sullivan, M. M.; Lewis, P. A.; Williams, L. A.; Camilleri, J. P.; Plant, M. J.; Coles, E. C. (1998). "A long-term five-year randomized controlled trial of hydroxychloroquine, sodium aurothiomalate, auranofin and penicillamine in the treatment of patients with rheumatoid arthritis". British journal of rheumatology 37 (9): 992–1002. doi:10.1093/rheumatology/37.9.992. PMID 9783766.  edit
  2. ^ Iqbal, M. S.; Saeed, M.; Taqi, S. G. (2008). "Erythrocyte Membrane Gold Levels After Treatment with Auranofin and Sodium Aurothiomalate". Biological Trace Element Research 126 (1–3): 56–64. doi:10.1007/s12011-008-8184-x. PMID 18649049.  edit