Sodium aurothiosulfate

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Sodium aurothiosulfate
Na3Au(S2O3)2.png
Sodium-gold(I)-thiosulfate-dihydrate-unit-cell-3D-balls.png
Systematic (IUPAC) name
trisodium dithiosulphate aurate(I), dihydrate
Clinical data
Legal status ?
Routes Intramuscular injection
Identifiers
CAS number 18497-75-1 YesY
ATC code M01CB02
PubChem CID 170028
Chemical data
Formula AuNa3O6S4 
Mol. mass 332.08452 g/mol
 YesY (what is this?)  (verify)

Sodium aurothiosulfate is the inorganic compound with the formula Na3Au(S2O3)2·2H2O. This salt contains an anionic linear coordination complex of gold(I) bound to two thiosulfate ligands.[1][2] Like several other gold compounds, this species is used as an antirheumatic.[3]The first placebo-controlled trial was probably conducted in 1931, when sanocrysin was compared with distilled water for the treatment of tuberculosis.[4]

References[edit]

  1. ^ Baggio, R (1973). "Crystal and molecular structure of trisodium dithiosulphate aurate(I), dihydrate, Na3[Au(S2O3)2],2H2O". Journal of Inorganic and Nuclear Chemistry 35 (9): 3191. doi:10.1016/0022-1902(73)80019-3. 
  2. ^ Tobön-Zapata, G (1997). "Vibrational spectrum of Sanocrysin". Spectrochimica Acta Part a Molecular and Biomolecular Spectroscopy 53 (2): 183. doi:10.1016/S1386-1425(97)83024-7. 
  3. ^ Shaw, III, C. F. (1999). "Gold-Based Therapeutic Agents". Chemical Reviews 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494. 
  4. ^ Ethical and regulatory aspects of clinical research: readings and commentary, Ezekiel J. Emanuel, Johns Hopkins University Press, 2003, p 140

Source of Chemical Formula: http://medical.merriam-webster.com/medical/gold%20sodium%20thiomalate