Solanum glaucophyllum is a species of the family Solanaceae. It is known as waxy-leaf nightshade.
It is an endemic plant of Brazil, Bolivia, Argentina, Paraguay and Uruguay.
It is usually classified under the Section Cyphomandropsis, within the subgenus Bassovia.
It is a rhizomatous plant with a simple stem and shortly branched, 1–2 m tall or more. Leaves simple, ovate, lanceolate, greenish-gray, 1-2 cm long, bluish purple flowers. The fruit is a globose berry 1–2 cm in diameter, blue-black, and features several seeds inside. It propagates vegetatively by gemmiferous roots of high regeneration capacity in water-saturated soils like edges of lakes.
Its consumption by ruminants produces an illness on them.