Somatostatin receptor 4

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Somatostatin receptor 4
Identifiers
Symbols SSTR4 ; SS-4-R; SS4-R; SS4R
External IDs OMIM182454 MGI105372 HomoloGene20286 IUPHAR: sst4 ChEMBL: 1853 GeneCards: SSTR4 Gene
RNA expression pattern
PBB GE SSTR4 214556 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 6754 20608
Ensembl ENSG00000132671 ENSMUSG00000037014
UniProt P31391 Q8BQ97
RefSeq (mRNA) NM_001052 NM_009219
RefSeq (protein) NP_001043 NP_033245
Location (UCSC) Chr 20:
23.02 – 23.02 Mb
Chr 2:
148.4 – 148.4 Mb
PubMed search [1] [2]

Somatostatin receptor type 4 is a protein that in humans is encoded by the SSTR4 gene.[1][2]

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.[2]

See also[edit]

References[edit]

  1. ^ Rohrer L, Raulf F, Bruns C, Buettner R, Hofstaedter F, Schule R (Jun 1993). "Cloning and characterization of a fourth human somatostatin receptor". Proc Natl Acad Sci U S A 90 (9): 4196–200. doi:10.1073/pnas.90.9.4196. PMC 46473. PMID 8483934. 
  2. ^ a b "Entrez Gene: SSTR4 somatostatin receptor 4". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.