Southpaw (disambiguation)
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Southpaw is another name for a left-handed individual, particularly in sports.
- Southpaw stance, the normal stance for a left-handed boxer
- Southpaw (Chicago White Sox mascot), a mascot of the Chicago White Sox
- The Southpaw, a 1952 baseball novel by Mark Harris
- "Southpaw" (Pink Lady song), a 1978 song by Pink Lady
- "Southpaw" (Morrissey song), the final track on Southpaw Grammar
- Southpaw (comics), a fictional character that first appeared in the Marvel comic She-Hulk
- Southpaw engine, a video game engine for the Game Boy Advance
- Southpaw (gene), a NODAL-related gene involved in left-right body patterning in vertebrates
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