|Germinal epithelium of the testicle.
1: basal lamina
3: spermatocyte 1st order
4: spermatocyte 2nd order
6: mature spermatid
7: Sertoli cell
8: tight junction (blood testis barrier)
|Transverse section of a tubule of the testis of a rat. × 250.|
|Gray's||subject #258 1243|
The spermatid is the haploid male gametid that results from division of secondary spermatocytes. As a result of meiosis, each spermatid contains only half of the genetic material present in the original primary spermatocyte.
Spermatids are connected by cytoplasmic material and have superfluous cytoplasmic material around their nuclei.
The spermatids begin to grow a living thread, develop a thickened mid-piece where the mitochondria become localised, and form an acrosome. Spermatid DNA also undergoes packaging, becoming highly condensed. The DNA is packaged firstly with specific nuclear basic proteins, which are subsequently replaced with protamines during spermatid elongation. The resultant tightly packed chromatin is transcriptionally inactive.
- BU Histology Learning System: 17804loa - "Male Reproductive System: testis, early spermatids"
- BU Histology Learning System: 17805loa - "Male Reproductive System: testis, late spermatids"
- Histology at okstate.edu