Sphingomyelin phosphodiesterase D

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Sphingomyelin phosphodiesterase D
Identifiers
EC number 3.1.4.41
CAS number 54992-31-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Sphingomyelin phosphodiesterase D (EC 3.1.4.41, sphingomyelinase D) is an enzyme with system name sphingomyelin ceramide-phosphohydrolase.[1][2] This enzyme catalyses the following chemical reaction

sphingomyelin + H2O \rightleftharpoons ceramide phosphate + choline

This enzyme hydrolyses 2-lysophosphatidylcholine to choline and 2-lysophosphatidate.

References[edit]

  1. ^ Carne, H.R.; Onon, Eleanor O. (19 January 1978). "Action of Corynebacterium ovis exotoxin on endothelial cells of blood vessels". Nature 271 (5642): 246–248. doi:10.1038/271246a0. PMID 622164. 
  2. ^ Souček, Andrej; Michalec, Čestmír; Součková, Anna (13 January 1971). "Identification and characterization of a new enzyme of the group “phospholipase D” isolated from Corynebacterium ovis". Biochimica et Biophysica Acta 227 (1): 116–128. doi:10.1016/0005-2744(71)90173-2. PMID 5543581. 

See also[edit]

External links[edit]