|Format||100 Pages, full color|
|Publication date||September 2006–January 2007 (monthly)|
|Number of issues||5|
|Main character(s)||Spike, Lorne|
|Letterer(s)||Michael Heisler, Sulaco Studios, Neil Uyetake, Chris Mowry|
|Colorist(s)||Matteo Gherardi, Elena Virzi, Fabio Mantovan, Donatella Melchionno|
Spike: Asylum is a five-issue comic book limited series based on Angel television series. It was released from September 2006 through January 2007. The five issues were collected together in a single trade paperback in May 2007.
Story description 
Ruby Monahan has gone missing and her family recruits Spike to track her down. It seems Ruby (a half-demon) has been checked into "Mosaic Wellness Center", a rehab facility designed to cure the demonic. In an unfortunate turn of events, Spike faces both the Mosaic Center, which hopes to cure his vampiric nature, and its clientele who want him dead.
Writing and artwork 
Cultural references 
- The Usual Suspects: A 1995 movie written by Christopher McQuarrie, directed by Bryan Singer, and starring Kevin Spacey. The cover for Asylum #2 is an homage to promotional material from this movie.
- Smallville: In Asylum #3, a character calls Spike Brainiac, a character that actor James Marsters played in season 5 of the television series about a young Superman.
- Firefly: When Lorne is seen performing in Las Vegas at the end of issue 3, he is performing the theme to Firefly, a Joss Whedon television show. Whedon is also the creator of both Buffy the Vampire Slayer and Angel.
- Ghostbusters: Ivo Shandor, the Gozerian cultist/architect, is named as the person who built the Mosaic Asylum. Specific lines from the movie are mentioned ("society being too sick to survive", etc.), and Spike muses on why the name is familiar to him.
In his blog, writer Brian Lynch has commented on when the comics takes place within Buffyverse continuity:
|“||Spike is in Los Angeles, and he has a soul, and he's up and about and able to touch (and punch and kick and bite...and also hug...I'd assume. Three issues in and he does not hug anyone. Maybe for SPIKE: ASYLUM summer annual). But beyond that, I'm just telling the best SPIKE story I can, timelines be damned. Pick up the series and you tell us when you think it is. The first correct answer gets a hug. From Spike.||”|
Canonical issues 
Angel comics are not usually considered by fans as canon. However unlike fanfic, 'overviews' summarising their story, written early in the writing process, were 'approved' by both Fox and Whedon (or his office), and the books were therefore later published as officially Angel merchandise.
Later, Betta George from Asylum appears in Lynch and Joss Whedon's canonical Angel: After the Fall. The Mosaic Wellness Center is seen briefly, and Spike refers to him and George as going "way back". Later references under Lynch's penas the series went on (such as in the After the Fall Epilogue in issue #23) would place the events of Spike: Asylum more definitively within the chronology of the series.
- Idwpublishing.com - Preview of first five pages (without dialogue)
- Whedonesque.com Whedonesquers discuss the comic (May 2006)
- Comicscontinuum.com - Lynch comments on his approach to writing (July 2006)