Spiroxatrine

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Spiroxatrine
Spiroxatrine.svg
Names
IUPAC name
8-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Identifiers
1054-88-2 N
ChEMBL ChEMBL300555 YesY
ChemSpider 5078 YesY
IUPHAR ligand 53
Jmol-3D images Image
MeSH Spiroxatrine
PubChem 5268
Properties
C22H25N3O3
Molar mass 379.45 g·mol−1
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Spiroxatrine is a drug which acts as a selective antagonist at both the 5-HT1A receptor and the α2C adrenergic receptor.[1] It is an analogue of spiperone, and also has some dopamine antagonist effects.

References[edit]

  1. ^ Terrón, J. A.; Ibarra, M; Ransanz, V; Hong, E; Villalón, C. M. (1993). "The alpha-antiadrenergic properties of spiroxatrine, a ligand of serotonergic 5-HT1A receptors". Archivos del Instituto de Cardiologia de Mexico 63 (4): 289–95. PMID 8105762.  edit