St. Helena Hospital is operated by Adventist Health, a group of 19 hospitals in the western United States, and is located in the Napa Valley, California, between the town of St. Helena, and the community of Angwin, which is home to Pacific Union College. St. Helena Hospital was established in 1878 as the Rural Health Retreat; it is the oldest Seventh-day Adventist hospital in the United States. After the turn of the century, St. Helena Hospital became a full-service community hospital. St. Helena Hospital operates St. Helena Hospital Clearlake in Lake County and a 61-bed behavioral health hospital in Vallejo, California that provides mental health care services for children, adolescents and adults across northern California. St. Helena Hospital has a teaching affiliation with Pacific Union College.
Heart & Vascular Center: A complete range of services includes two state-of-the-art cardiac cath labs, a nationally recognized heart surgery program, leading-edge peripheral vascular techniques, and an outpatient cardiovascular rehabilitation program.
Medical/Surgical Services: A broad scope of services includes minimally invasive, thoracic, orthopedic, urological, OB/GYN, plastic/reconstructive surgery, gastro-intestinal laboratory and medically monitored and intensive care.
Emergency Care Center: 24-hour emergency medical services are provided, including treatment for cardiovascular events such as heart attack. The ER is a "No-Wait" ER  which provides medical care immediately upon arrival. The center has a helipad, serves as a Safe Baby drop point and was rated number one for overall care received by patients.
St. Helena Recovery Center: Residential and outpatient programs for alcohol and chemical abuse, including medical detoxification.
St. Helena Center for Health: The St. Helena Center for Health opened in 1969, maintaining the hospital’s emphasis on whole-person wellness. The center offers an innovative preventive and wellness program called TakeTEN™ which includes diabetes care, cardiovascular disease care, weight management, mystery disease diagnosis and smoking cessation through their Smoke-Free Life program.
The Martin-O'Neil Cancer Center: Diagnosis, surgery and treatment of cancer including oncology as well as clinical research trials in consort with the University of California San Francisco. The center is a resource for complete cancer care and integrative health services which includes a patient restoration area and therapy spa that offers massage therapy, yoga, nutritional therapy and other helpful offerings. The center also offers spiritual counseling, nutrition consultations, support services, and a cancer resource library.
Obstetrics: The Family Birth Place at St. Helena Hospital delivers approximately 300 newborns a year.
Behavioral Health: The St. Helena Hospital Center for Behavioral Health in Vallejo provides child, adolescent and adult inpatient treatment, adult partial hospitalization, and intensive outpatient care. The St. Helena Hospital campus offers adult inpatient care. Silverado Psychiatric Center in Calistoga offers adult outpatient care.
Sleep Disorders Center: An advanced diagnostic center features four comfortable, hotel-like rooms for diagnosing sleep disorders.
Women's Services: The St. Helena Women’s Center opened in St. Helena in 2011 and employs top doctors including a plastic surgeon, a medical esthetician, a female urologist, a certified Nurse Midwife and a Certified Menopause Specialist. They also provide Obstetrics & Gynecology care, including vaginal and pelvic reconstructive surgeries from top OB/GYN doctors including Dr. Michael S. Baggish, the co-author of “Atlas of Pelvic Anatomy and Gynecological Surgery”. Obstetrics and Gynecological services are also extended to Napa, Clearlake and Hidden Valley Lake. The Women's Center also offers mammography and bone density testing.