The minster was built c. 1060 on the site of an earlier church, and is dedicated to St Gregory, who was Pope 590–604.
The church is open during the day and for evening services with volunteer stewards helping visitors on summer weekends. The maintenance of the fabric of the building is helped by financial contributions from The Friends of St Gregory's Minster. The Friends Annual General Meeting is followed by the Kirkdale Lecture about the parish and its environs.
The Parish of Kirkdale is a Local Ecumenical Partnership with the church of St Hilda's, Beadlam.