Located in Walthamstow, St James Street station opens onto the street of the same name. This section of the A1006 is the local high street. Shoppers have an easy route from the southernmost end of the market to the railway station, which provides a fast and regular route to the top of the market (Walthamstow Central) or into Liverpool Street.
After the transfer of the "West Anglian" portion of the former WAGN franchise to National Express East Anglia, the station was redeveloped. A dual staircase was constructed, allowing passengers to access the train platform without passing through the main body of the station itself, and permitting the ticket office to be locked up overnight.