"Still D.R.E." was released on October 13, 1999 as the lead single from Dr Dre's second multi-platinum studio album, The Chronic 2001. The song, co-written by Jay-Z, features vocals from Snoop Dogg on the intro, chorus and outro. The song sold over 4,000,000 copies and was eventually certified 4x Platinum by RIAA. The single was popular, helping the album reach multi-platinum status, announcing Dre's return to the forefront of the hip-hop scene. "Still D.R.E." debuted at number 93 on the Billboard Hot 100. It was more successful in the United Kingdom, where it peaked at #6. The song featured in the in-game radio station West Coast Classics in the video game Grand Theft Auto V. The song is also used in series 1 and 2 of Prison Break.
The music video, directed by Hype Williams, consists mainly of The D.O.C., Snoop Dogg and Dr. Dre driving and riding in lowrider cars (a reference to the "Nuthin' But a 'G' Thang" music video from The Chronic album). It features a cameo from Eminem, seen chasing a group of females across a beach when Dre raps, "Kept my ear to the streets, signed Eminem, he's triple platinum, doing fifty a week." Xzibit is also shown driving a car towards the end of the music video.