Stratum lucidum

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Histologic image showing a section of epidermis. Stratum lucidum labeled near center.
Section of epidermis

The stratum lucidum (Latin for "clear layer") is a thin, clear layer of dead skin cells in the epidermis named for its translucent appearance under a microscope. It is found only in areas of thick skin, most noticeably on the palms of the hands and the soles of the feet.[1][2]

Located between the stratum granulosum and stratum corneum layers, it is composed of three to five layers of dead, flattened keratinocytes.[3][4] The keratinocytes of the stratum lucidum do not feature distinct boundaries and are filled with eleidin, an intermediate form of keratin.

The thickness of the lucidum is controlled by the rate of mitosis of the epidermal cells. In addition, melanocytes determine the darkness of the stratum lucidum. The cells of the stratum lucidum are flattened and contain an oily substance that is the result of exocytosis of lamellar bodies accumulated while the keratinocytes are moving through the stratum spinosum and stratum granulosum.

[edit] References

  1. ^ http://books.google.com/books?id=80rSnSZWFhMC&pg=PA41
  2. ^ http://books.google.com/books?id=wyFYTCus8OgC&pg=PA376
  3. ^ McGrath, J.A.; Eady, R.A.; Pope, F.M. (2004). Rook's Textbook of Dermatology (Seventh Edition). Blackwell Publishing. Pages 3.8. ISBN 9780632064298.
  4. ^ Tortora, Gerard; Derrickson, Bryan; Principles of Anatomy and Physiology (2009)152 John Wiley & Sons Inc, Hoboken, NJ ISBN978-0-470-08471-7.
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