Streptogrisin A

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Streptogrisin A
EC number
CAS number 55326-50-6
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Streptogrisin A (EC, Streptomyces griseus protease A, protease A, proteinase A, Streptomyces griseus proteinase A, Streptomyces griseus serine proteinase 3, Streptomyces griseus serine proteinase A) is an enzyme.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with specificity similar to chymotrypsin

This enzyme is isolated from Streptomyces griseus.


  1. ^ Johnson, P. and Smillie, L.B. (1971). "The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus". Can. J. Biochem. 49: 548–562. doi:10.1139/o71-082. PMID 5575653. 
  2. ^ Sielecki, A.R., Hendrickson, W.A., Broughton, C.G., Delbaere, L.T.J., Brayer, G.D. and James, M.N.G. (1979). "Protein structure refinement: Streptomyces griseus serine protease A at 1.8 Å resolution". J. Mol. Biol. 134: 781–804. doi:10.1016/0022-2836(79)90486-8. PMID 119870. 
  3. ^ James, M.N.G., Sielecki, A.R., Brayer, G.D., Delbaere, L.T.J. and Bauer, C.-A. (1980). "Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 Å resolution". J. Mol. Biol. 144: 43–88. doi:10.1016/0022-2836(80)90214-4. PMID 6783761. 
  4. ^ Delbaere, L.T.J. and Brayer, G.D. (1985). "The 1.8 Å structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates". J. Mol. Biol. 183: 89–103. doi:10.1016/0022-2836(85)90283-9. PMID 3892018. 
  5. ^ Henderson, G., Krygsman, P., Liu, C.J., Davey, C.C. and Malek, L.T. (1987). "Characterization and structure of genes for proteases A and B from Streptomyces griseus". J. Bacteriol. 169: 3778–3784. PMID 3112129. 

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