In March 2005 he had a number one single on the UK Dance Chart with "X-Ray / Scarecrow". The single reached number 60 on the UK Singles Chart. In June 2008, he hit number one on the UK Dance Chart again with "Timewarp / Join the Dots".
In 2010, Sub Focus was a support act for Australian drum & bass band Pendulum on their UK tour to promote their third album Immersion. Later that year, he produced the Example track "Kickstarts" for his second album, Won't Go Quietly. The track was successful in the UK Singles Chart, peaking at #3. This makes it Sub Focus' most commercially successful production to date. A free track "Falling Down" featuring vocals from Kenzie May was released on his website and was later released digitally as an EP. In 2012, he released "Out the Blue" featuring Alice Gold and it reached #23 in the UK Singles Chart. It was followed by "Tidal Wave" featuring Alpines which peaked at #12 in the UK Singles Chart, which also became his first to spend at least 2 weeks in the Top 40. Tidal Wave also featured on the Mercedes Benz "Sound with Power" advertising campaign, along with Tinie Tempah. On 12 May 2013, "Endorphins" featuring Alex Clare was released, continuing his recent chart success, peaking at #10 in the UK Singles Chart. The album's fifth single "Turn It Around" was released on 22 September 2013 and reached #14. His second studio album Torus was released on 30 September 2013. He headlined the Radio 1 Dance stage at the Reading and Leeds Festivals 2013. Sub Focus played at Glastonbury 2013 with his new live show setup. Later in the summer of 2013 he went on to play at Dour Festival, Reading & Leeds, Global Gathering, Bestival and Isle of Wight festival among others. He headlined BBC Radio 1Xtra Live at the Bournemouth International Centre on 7 October. He then completed a 2013 UK tour. The sixth single from Torus, "Turn Back Time", slowly climbed the UK Singles Chart to number 10. The next single from Torus, a new version of "Close" featuring a session singer instead of MNEK, failed to chart.