Succinyl-diaminopimelate desuccinylase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
succinyl-diaminopimelate desuccinylase
Identifiers
EC number 3.5.1.18
CAS number 9024-94-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) is an enzyme that catalyzes the chemical reaction

N-succinyl-LL-2,6-diaminoheptanedioate + H2O \rightleftharpoons succinate + LL-2,6-diaminoheptanedioate

Thus, the two substrates of this enzyme are N-succinyl-LL-2,6-diaminoheptanedioate and H2O, whereas its two products are succinate and LL-2,6-diaminoheptanedioate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase. This enzyme is also called N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase. This enzyme participates in lysine biosynthesis.

References[edit]

  • Kindler SH and Gilvarg C (1960). "N-Succinyl-L-2,6-diaminopimelic acid deacylase". J. Biol. Chem. 235: 3532–3535. PMID 13756049.