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Systematic (IUPAC) name
4-amino-N-pyrimidin- 2-yl-benzenesulfonamide
Clinical data
AHFS/ monograph
MedlinePlus a682130
  •  ?
  • (Prescription only)
Topical cream, oral
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Half-life ?
Excretion ?
68-35-9 YesY
J01EC02 QJ01EQ10
PubChem CID 5215
DrugBank DB00359 N
ChemSpider 5026 N
UNII 0N7609K889 N
KEGG D00587 YesY
Chemical data
Formula C10H10N4O2S
250.278 g/mol
 N (what is this?)  (verify)

Sulfadiazine is a sulfonamide antibiotic.

It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.[1]

Medical uses[edit]

It eliminates bacteria that cause infections by stopping the production of folate inside the bacterial cell, and is commonly used to treat urinary tract infections.

In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii.

Side effects[edit]

Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.

Brand names[edit]

Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid

See also[edit]


  1. ^ "WHO Model List of EssentialMedicines" (PDF). World Health Organization. October 2013. Retrieved 22 April 2014.