Sulfadimethoxine

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Sulfadimethoxine
Sulfadimethoxine.svg
Sulfadimethoxine ball-and-stick model.png
Systematic (IUPAC) name
4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
Clinical data
AHFS/Drugs.com FDA Professional Drug Information
Legal status
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Identifiers
CAS number 122-11-2 YesY
ATC code J01ED02 QJ01EQ09 QP51AG02
PubChem CID 5323
DrugBank DB06150
ChemSpider 5132 YesY
UNII 30CPC5LDEX YesY
KEGG D01142 YesY
ChEBI CHEBI:32161 YesY
ChEMBL CHEMBL62193 YesY
Chemical data
Formula C12H14N4O4S 
Mol. mass 310.33 g/mol
 YesY (what is this?)  (verify)

Sulfadimethoxine (trade name Di-Methox, Albon) is a sulfonamide antibiotic. Albon is produced by Pfizer Animal Health and is available as an oral suspension, tablet or bolus. It is used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.[5] It is most frequently used in veterinary medicine. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. It is also commonly used for the treatment of coccidiosis in many species.[1]

Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully used there for more than 35 years.[2] It is widely available in Russia as an over-the-counter drug manufactured by a number of Russian pharmaceutical companies.

Side Effects[edit]

Some side effects include:

  • Redness of the eye[3]
  • Discharge from the eye
  • Other symptoms related to the eye
  • Bleeding
  • Vomiting and diarrhea
  • Increased thirst is common[4]
  • Incessant itch

Animals should be kept well hydrated to prevent the formation of sulfa crystals in the animal's urine.[6]

Uses[edit]

It can be used for:[5]

  • metritis
  • tonsillitis
  • pharyngitis
  • pneumonia
  • pyometra
  • anal gland infections
  • dermatitis
  • wounds and abscesses
  • enteritis
  • salmonellosis
  • enteritis associated with coccidiosis in dogs

Actions[edit]

It has been shown to be effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.

Notes[edit]

External links[edit]