Survival of motor neuron protein-interacting protein 1
From Wikipedia, the free encyclopedia
Survival of motor neuron protein-interacting protein 1 is a protein that in humans is encoded by the SIP1 gene.[1][2][3]
[edit] Interactions
Survival of motor neuron protein-interacting protein 1 has been shown to interact with DDX20[4][5] and SMN1.[6][7][2]
[edit] See also
[edit] References
- ^ Fischer U, Liu Q, Dreyfuss G (Oct 1997). "The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis". Cell 90 (6): 1023–9. doi:10.1016/S0092-8674(00)80368-2. PMID 9323130.
- ^ a b Liu Q, Fischer U, Wang F, Dreyfuss G (Oct 1997). "The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins". Cell 90 (6): 1013–21. doi:10.1016/S0092-8674(00)80367-0. PMID 9323129.
- ^ "Entrez Gene: SIP1 survival of motor neuron protein interacting protein 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8487.
- ^ Mourelatos, Zissimos; Dostie Josée, Paushkin Sergey, Sharma Anup, Charroux Bernard, Abel Linda, Rappsilber Juri, Mann Matthias, Dreyfuss Gideon (Mar. 2002). "miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs". Genes Dev. (United States) 16 (6): 720–8. doi:10.1101/gad.974702. ISSN 0890-9369. PMC 155365. PMID 11914277. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=155365.
- ^ Charroux, B; Pellizzoni L, Perkinson R A, Shevchenko A, Mann M, Dreyfuss G (Dec. 1999). "Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems". J. Cell Biol. (UNITED STATES) 147 (6): 1181–94. doi:10.1083/jcb.147.6.1181. ISSN 0021-9525. PMC 2168095. PMID 10601333. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2168095.
- ^ Carnegie, Graeme K; Sleeman Judith E, Morrice Nick, Hastie C James, Peggie Mark W, Philp Amanda, Lamond Angus I, Cohen Patricia T W (May. 2003). "Protein phosphatase 4 interacts with the Survival of motor neurons complex and enhances the temporal localisation of snRNPs". J. Cell. Sci. (England) 116 (Pt 10): 1905–13. doi:10.1242/jcs.00409. ISSN 0021-9533. PMID 12668731.
- ^ Meister, G; Bühler D, Laggerbauer B, Zobawa M, Lottspeich F, Fischer U (Aug. 2000). "Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins". Hum. Mol. Genet. (ENGLAND) 9 (13): 1977–86. doi:10.1093/hmg/9.13.1977. ISSN 0964-6906. PMID 10942426.
[edit] Further reading
- Wang Z, Wu X, Friedberg EC (1997). "Molecular mechanism of base excision repair of uracil-containing DNA in yeast cell-free extracts". J. Biol. Chem. 272 (38): 24064–71. doi:10.1074/jbc.272.38.24064. PMID 9295360.
- Zhang WJ, Wu JY (1998). "Sip1, a Novel RS Domain-Containing Protein Essential for Pre-mRNA Splicing". Mol. Cell. Biol. 18 (2): 676–84. PMC 108778. PMID 9447963. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=108778.
- Charroux B, Pellizzoni L, Perkinson RA, et al. (2000). "Gemin3: A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems". J. Cell Biol. 147 (6): 1181–94. doi:10.1083/jcb.147.6.1181. PMC 2168095. PMID 10601333. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2168095.
- Charroux B, Pellizzoni L, Perkinson RA, et al. (2000). "Gemin4: A Novel Component of the Smn Complex That Is Found in Both Gems and Nucleoli". J. Cell Biol. 148 (6): 1177–86. doi:10.1083/jcb.148.6.1177. PMC 2174312. PMID 10725331. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2174312.
- Helmken C, Wetter A, Rudnik-Schöneborn S, et al. (2000). "An essential SMN interacting protein (SIP1) is not involved in the phenotypic variability of spinal muscular atrophy (SMA)". Eur. J. Hum. Genet. 8 (7): 493–9. doi:10.1038/sj.ejhg.5200479. PMID 10909848.
- Meister G, Bühler D, Laggerbauer B, et al. (2000). "Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins". Hum. Mol. Genet. 9 (13): 1977–86. doi:10.1093/hmg/9.13.1977. PMID 10942426.
- Young PJ, Man NT, Lorson CL, et al. (2001). "The exon 2b region of the spinal muscular atrophy protein, SMN, is involved in self-association and SIP1 binding". Hum. Mol. Genet. 9 (19): 2869–77. doi:10.1093/hmg/9.19.2869. PMID 11092763.
- Selenko P, Sprangers R, Stier G, et al. (2001). "SMN tudor domain structure and its interaction with the Sm proteins". Nat. Struct. Biol. 8 (1): 27–31. doi:10.1038/83014. PMID 11135666.
- Pellizzoni L, Charroux B, Rappsilber J, et al. (2001). "A Functional Interaction between the Survival Motor Neuron Complex and RNA Polymerase II". J. Cell Biol. 152 (1): 75–85. doi:10.1083/jcb.152.1.75. PMC 2193649. PMID 11149922. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2193649.
- Jablonka S, Bandilla M, Wiese S, et al. (2001). "Co-regulation of survival of motor neuron (SMN) protein and its interactor SIP1 during development and in spinal muscular atrophy". Hum. Mol. Genet. 10 (5): 497–505. doi:10.1093/hmg/10.5.497. PMID 11181573.
- Friesen WJ, Massenet S, Paushkin S, et al. (2001). "SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets". Mol. Cell 7 (5): 1111–7. doi:10.1016/S1097-2765(01)00244-1. PMID 11389857.
- Park JW, Voss PG, Grabski S, et al. (2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic Acids Res. 29 (17): 3595–602. doi:10.1093/nar/29.17.3595. PMC 55878. PMID 11522829. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=55878.
- Friesen WJ, Paushkin S, Wyce A, et al. (2001). "The Methylosome, a 20S Complex Containing JBP1 and pICln, Produces Dimethylarginine-Modified Sm Proteins". Mol. Cell. Biol. 21 (24): 8289–300. doi:10.1128/MCB.21.24.8289-8300.2001. PMC 99994. PMID 11713266. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=99994.
- Gubitz AK, Mourelatos Z, Abel L, et al. (2002). "Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins". J. Biol. Chem. 277 (7): 5631–6. doi:10.1074/jbc.M109448200. PMID 11714716.
- Pellizzoni L, Baccon J, Rappsilber J, et al. (2002). "Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component". J. Biol. Chem. 277 (9): 7540–5. doi:10.1074/jbc.M110141200. PMID 11748230.
- Aerbajinai W, Ishihara T, Arahata K, Tsukahara T (2002). "Increased expression level of the splicing variant of SIP1 in motor neuron diseases". Int. J. Biochem. Cell Biol. 34 (6): 699–707. doi:10.1016/S1357-2725(01)00150-9. PMID 11943600.
- Baccon J, Pellizzoni L, Rappsilber J, et al. (2002). "Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex". J. Biol. Chem. 277 (35): 31957–62. doi:10.1074/jbc.M203478200. PMID 12065586.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
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Envelope (membrane)/
nuclear lamina |
Pore complex: Nucleoporin ( NUP35, NUP37, NUP43, NUP50, NUP54, NUP62, NUP85, NUP88, NUP93, NUP98, NUP107, NUP133, NUP153, NUP155, NUP160, NUP188, NUP205, NUP210, NUP214) · AAAS
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| Nucleolus |
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Chromatin · Dot (PML body) · Paraspeckle
SMC protein: Cohesin (SMC1A, SMC1B, SMC3) · Condensin (NCAPD2, NCAPD3, NCAPG, NCAPG2, NCAPH, NCAPH2, SMC2, SMC4) · DNA repair (SMC5, SMC6)
Transition nuclear protein: TNP1, TNP2
Nuclear matrix · Nucleoplasm · Nucleoskeleton · Nucleosol
LITAF
see also transcription factors and intracellular receptors
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