The station first opened as Sano Station (佐野駅?) under the Japanese Government Railways (JGR), (the predecessor to the post-war Japanese National Railways) on February 1, 1889. It was renamed Susono Station on July 15, 1915. After the opening of the Tanna Tunnel on December 1, 1934, it became a station of the Gotemba Line. Regularly scheduled freight services were discontinued on March 10, 1974 and baggage-handling services from February 1, 1984. Along with its division and privatization of JNR on April 1, 1987, the station came under the control and operation of JR Central.