The Syracuse Silver Knights' first season of play began in 2011–12, when they joined the MISL as an expansion franchise. For their inaugural season, the Silver Knights played their home games at the Oncenter War Memorial Arena in downtownSyracuse.
The team finished third in the Eastern Division in 2012, having been eliminated from playoff contention when the Rochester Lancers beat the Wichita Wings on February 23, 2012.
In 2013, the Silver Knight foundation was launched to help benefit kids in tough economic and social situations. The foundation hosts events throughout the year which helps raise money for these children. Many Silver Knights players, including reserve and U19 players, volunteer their time to help partake in the events.
After the 2013-2014 season, the team announced that it was leaving the MISL along with five other teams and join the PASL, which was subsequently renamed the MASL
The Silver Knights also have a youth team. Local youth team CNY United was given permission by Tommy Tanner become "Syracuse Silver Knights U19". They are coached by Silver Knights assistant coach Joe Papaleo and Silver Knights first team player LJ Papaleo.