From Wikipedia, the free encyclopedia
Jump to: navigation, search
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
Symbols TAF3 ; TAF140; TAFII-140; TAFII140
External IDs OMIM606576 MGI2388097 HomoloGene35415 GeneCards: TAF3 Gene
RNA expression pattern
PBB GE TAF3 gnf1h05253 s at tn.png
PBB GE TAF3 gnf1h06476 at tn.png
PBB GE TAF3 gnf1h10566 at tn.png
More reference expression data
Species Human Mouse
Entrez 83860 209361
Ensembl ENSG00000165632 ENSMUSG00000025782
UniProt Q5VWG9 Q5HZG4
RefSeq (mRNA) NM_031923 NM_027748
RefSeq (protein) NP_114129 NP_082024
Location (UCSC) Chr 10:
7.86 – 8.06 Mb
Chr 2:
9.91 – 10.05 Mb
PubMed search [1] [2]

The TAF3 protein is part of the basal transcription factor TFIID. Recently it was shown that a PHD finger in the C-terminus of the protein directly binds to trimethylated histone H3 lysine four, a histone mark associated with promoters that are actively being transcribed. Transcription initiation factor TFIID subunit 3 is a protein that in humans is encoded by the TAF3 gene.[1][2][3]


Further reading[edit]