TAS2R13

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Taste receptor, type 2, member 13
Identifiers
Symbols TAS2R13 ; T2R13; TRB3
External IDs OMIM604792 MGI2681259 HomoloGene41542 IUPHAR: TAS2R13 GeneCards: TAS2R13 Gene
Orthologs
Species Human Mouse
Entrez 50838 387349
Ensembl ENSG00000212128 ENSMUSG00000071150
UniProt Q9NYV9 Q7M720
RefSeq (mRNA) NM_023920 NM_207024
RefSeq (protein) NP_076409 NP_996907
Location (UCSC) Chr 12:
11.06 – 11.06 Mb
Chr 6:
132.7 – 132.7 Mb
PubMed search [1] [2]

Taste receptor type 2 member 13 is a protein that in humans is encoded by the TAS2R13 gene.[1][2][3]

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.[3]

See also[edit]

References[edit]

  1. ^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (Apr 2000). "A novel family of mammalian taste receptors". Cell 100 (6): 693–702. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934. 
  2. ^ Matsunami H, Montmayeur JP, Buck LB (Apr 2000). "A family of candidate taste receptors in human and mouse". Nature 404 (6778): 601–4. doi:10.1038/35007072. PMID 10766242. 
  3. ^ a b "Entrez Gene: TAS2R13 taste receptor, type 2, member 13". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.