TAS2R4

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Taste receptor, type 2, member 4
Identifiers
Symbols TAS2R4 ; T2R4
External IDs OMIM604869 MGI2681210 HomoloGene49480 IUPHAR: TAS2R4 GeneCards: TAS2R4 Gene
RNA expression pattern
PBB GE TAS2R4 221392 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 50832 57253
Ensembl ENSG00000127364 ENSMUSG00000037140
UniProt Q9NYW5 Q9JKT3
RefSeq (mRNA) NM_016944 NM_020502
RefSeq (protein) NP_058640 NP_065248
Location (UCSC) Chr 7:
141.48 – 141.48 Mb
Chr 6:
40.49 – 40.49 Mb
PubMed search [1] [2]

Taste receptor type 2 member 4 is a protein that in humans is encoded by the TAS2R4 gene.[1][2][3]

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception.[3]

See also[edit]

References[edit]

  1. ^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (Apr 2000). "A novel family of mammalian taste receptors". Cell 100 (6): 693–702. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934. 
  2. ^ Chandrashekar J, Mueller KL, Hoon MA, Adler E, Feng L, Guo W, Zuker CS, Ryba NJ (Apr 2000). "T2Rs function as bitter taste receptors". Cell 100 (6): 703–11. doi:10.1016/S0092-8674(00)80706-0. PMID 10761935. 
  3. ^ a b "Entrez Gene: TAS2R4 taste receptor, type 2, member 4". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.