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TCA may refer to:
- True cost accounting, a method of accounting which seeks to calculate the social, environmental, and economic costs and benefits of a product over its lifespan instead of focusing solely on the cost of its initial purchase.
- Transaction cost analysis, a method of determining the effectiveness of financial investment portfolio transactions.
- Trichromatic Colour Analyser, a software system that turns scanners into colorimeters
- Trichloroacetic acid, chemical used to precipitate protein in serum
- Taurocholic acid, a bile acid involved in the emulsification of fats
- Tricyclic antidepressant, a class of anti-depressant drugs
- 2,4,6-Trichloroanisole, a chemical compound which is the cause of cork taint in wine
- Citric acid cycle, or tricarboxylic acid cycle, a pathway in cellular metabolism
- Theoretical Chemistry Accounts
- Television Critics Association
- Thyroid Cancer Alliance
- Total Community Action
- Trans-Canada Air Lines
- Taiwanese Cultural Association
- Train Collectors Association
- Transportes Carga Aérea, a defunct Brazilian airline
- Trinity Christian Academy (disambiguation)
In other uses:
- Advanced Telecommunications Computing Architecture, a specification set for carrier grade communications equipment
- Terminal Control Area, a volume of controlled airspace
- Teen Choice Awards
- The Competition Authority (Ireland)
- Total cost of acquisition
- Toxin complex a, an insecticidal toxin complex in the bacterium Photorhabdus luminescens
- The Canadian Amateur, a magazine for amateur radio enthusiasts
- Transport Construction Authority, a former agency of the Government of New South Wales with responsibility for new railway projects in the city of Sydney, Australia
- Turks and Caicos Islands, from its ISO 3166-1 country code
TCA also refers to The Classical Academy, a school in Escondido.
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