Transcriptional enhancer factor TEF-3 is a protein that in humans is encoded by the TEAD4gene.
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
^Jacquemin P, Depetris D, Mattei MG, Martial JA, Davidson I (Mar 1999). "Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis". Genomics55 (1): 127–9. doi:10.1006/geno.1998.5628. PMID9889009.
^Stewart AF, Richard CW 3rd, Suzow J, Stephan D, Weremowicz S, Morton CC, Adra CN (Feb 1997). "Cloning of human RTEF-1, a transcriptional enhancer factor-1-related gene preferentially expressed in skeletal muscle: evidence for an ancient multigene family". Genomics37 (1): 68–76. doi:10.1006/geno.1996.0522. PMID8921372.
Hsu DK, Guo Y, Alberts GF et al. (1996). "Identification of a murine TEF-1-related gene expressed after mitogenic stimulation of quiescent fibroblasts and during myogenic differentiation". J. Biol. Chem.271 (23): 13786–95. doi:10.1074/jbc.271.23.13786. PMID8662936.
Jacquemin P, Hwang JJ, Martial JA et al. (1996). "A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain". J. Biol. Chem.271 (36): 21775–85. doi:10.1074/jbc.271.36.21775. PMID8702974.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID9373149.
Vaudin P, Delanoue R, Davidson I et al. (1999). "TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation". Development126 (21): 4807–16. PMID10518497.