TFAP4

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Transcription factor AP-4 (activating enhancer binding protein 4)
Identifiers
Symbols TFAP4 ; AP-4; bHLHc41
External IDs OMIM600743 MGI103239 HomoloGene2424 GeneCards: TFAP4 Gene
RNA expression pattern
PBB GE TFAP4 205688 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7023 83383
Ensembl ENSG00000090447 ENSMUSG00000005718
UniProt Q01664 Q9JIZ5
RefSeq (mRNA) NM_003223 NM_031182
RefSeq (protein) NP_003214 NP_112459
Location (UCSC) Chr 16:
4.31 – 4.32 Mb
Chr 16:
4.54 – 4.56 Mb
PubMed search [1] [2]

Transcription factor AP-4 (activating enhancer binding protein 4), also known as TFAP4, is a protein which in humans is encoded by the TFAP4 gene.[1]

Function[edit]

Transcription factor AP4 is a member of the basic helix-loop-helix (bHLH) transcription factors, which bind to the E-box sequence in the promoters of their target genes. AP-4 has been shown to act both as a repressor and an activator for different target genes.

References[edit]

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.