Transferrin receptor protein 1 (TfR1) also known as (Cluster of Differentiation 71) (CD71) is a protein that in humans is encoded by the TFRCgene. TfR1 is required for iron delivery from transferrin to cells.
CD71 as a potential new target in cases of human leukomia & lymphoma. InatherYs, in Evry, France, developed a candidate drug, INA01 antibody (anti-CD71) that showed its efficacy in pre-clinical studies in the therapy of two incurable orphan oncohematological diseases: the adult T cell leukemia (ATLL) caused by HTLV-1 and the Mantle cell lymphoma (MCL).
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