TGFB1I1

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Transforming growth factor beta 1 induced transcript 1
Identifiers
Symbols TGFB1I1 ; ARA55; HIC-5; HIC5; TSC-5
External IDs OMIM602353 MGI102784 HomoloGene7572 GeneCards: TGFB1I1 Gene
RNA expression pattern
PBB GE TGFB1I1 209651 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7041 21804
Ensembl ENSG00000140682 ENSMUSG00000030782
UniProt O43294 Q62219
RefSeq (mRNA) NM_001042454 NM_001289550
RefSeq (protein) NP_001035919 NP_001276479
Location (UCSC) Chr 16:
31.48 – 31.49 Mb
Chr 7:
128.25 – 128.25 Mb
PubMed search [1] [2]

Transforming growth factor beta-1-induced transcript 1 protein is a protein that in humans is encoded by the TGFB1I1 gene.[1][2]


Interactions[edit]

TGFB1I1 has been shown to interact with PTPN12,[3] PTK2,[1][4][5] Androgen receptor,[6][7] PTK2B,[1][5][6] Dopamine transporter[8] and Hsp27.[9]

See also[edit]

References[edit]

  1. ^ a b c Matsuya M, Sasaki H, Aoto H, Mitaka T, Nagura K, Ohba T, Ishino M, Takahashi S, Suzuki R, Sasaki T (February 1998). "Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions". J Biol Chem 273 (2): 1003–14. doi:10.1074/jbc.273.2.1003. PMID 9422762. 
  2. ^ Fujimoto N, Yeh S, Kang HY, Inui S, Chang HC, Mizokami A, Chang C (April 1999). "Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate". J Biol Chem 274 (12): 8316–21. doi:10.1074/jbc.274.12.8316. PMID 10075738. 
  3. ^ Nishiya, N; Iwabuchi Y; Shibanuma M; Côté J F; Tremblay M L; Nose K (April 1999). "Hic-5, a paxillin homologue, binds to the protein-tyrosine phosphatase PEST (PTP-PEST) through its LIM 3 domain". J. Biol. Chem. (UNITED STATES) 274 (14): 9847–53. doi:10.1074/jbc.274.14.9847. ISSN 0021-9258. PMID 10092676. 
  4. ^ Nishiya, N; Tachibana K; Shibanuma M; Mashimo J I; Nose K (August 2001). "Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase". Mol. Cell. Biol. (United States) 21 (16): 5332–45. doi:10.1128/MCB.21.16.5332-5345.2001. ISSN 0270-7306. PMC 87257. PMID 11463817. 
  5. ^ a b Thomas, S M; Hagel M; Turner C E (January 1999). "Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin". J. Cell. Sci. (ENGLAND) 112 (2): 181–90. ISSN 0021-9533. PMID 9858471. 
  6. ^ a b Wang, Xin; Yang Yue; Guo Xiaojian; Sampson Erik R; Hsu Cheng-Lung; Tsai Meng-Yin; Yeh Shuyuan; Wu Guan; Guo Yinglu; Chang Chawnshang (May 2002). "Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator". J. Biol. Chem. (United States) 277 (18): 15426–31. doi:10.1074/jbc.M111218200. ISSN 0021-9258. PMID 11856738. 
  7. ^ He, Bin; Minges John T; Lee Lori W; Wilson Elizabeth M (March 2002). "The FXXLF motif mediates androgen receptor-specific interactions with coregulators". J. Biol. Chem. (United States) 277 (12): 10226–35. doi:10.1074/jbc.M111975200. ISSN 0021-9258. PMID 11779876. 
  8. ^ Carneiro, Ana M; Ingram Susan L; Beaulieu Jean-Martin; Sweeney Ava; Amara Susan G; Thomas Sheila M; Caron Marc G; Torres Gonzalo E (August 2002). "The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter". J. Neurosci. (United States) 22 (16): 7045–54. PMID 12177201. 
  9. ^ Jia, Y; Ransom R F; Shibanuma M; Liu C; Welsh M J; Smoyer W E (October 2001). "Identification and characterization of hic-5/ARA55 as an hsp27 binding protein". J. Biol. Chem. (United States) 276 (43): 39911–8. doi:10.1074/jbc.M103510200. ISSN 0021-9258. PMID 11546764. 

External links[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.