THBS4

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Thrombospondin 4
Identifiers
Symbols THBS4 ; TSP4
External IDs OMIM600715 MGI1101779 HomoloGene20691 GeneCards: THBS4 Gene
RNA expression pattern
PBB GE THBS4 204776 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7060 21828
Ensembl ENSG00000113296 ENSMUSG00000021702
UniProt P35443 Q9Z1T2
RefSeq (mRNA) NM_003248 NM_011582
RefSeq (protein) NP_003239 NP_035712
Location (UCSC) Chr 5:
79.29 – 79.38 Mb
Chr 13:
92.75 – 92.79 Mb
PubMed search [1] [2]

Thrombospondin-4 is a protein that in humans is encoded by the THBS4 gene.[1][2]

The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. Studies of the rat counterpart suggest that this protein may be involved in local signaling in the developing and adult nervous system.[2]

References[edit]

  1. ^ Lawler J, McHenry K, Duquette M, Derick L (Mar 1995). "Characterization of human thrombospondin-4". J Biol Chem 270 (6): 2809–14. doi:10.1074/jbc.270.6.2809. PMID 7852353. 
  2. ^ a b "Entrez Gene: THBS4 thrombospondin 4". 

Further reading[edit]