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Tight junction protein 3
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols TJP3 ; ZO-3; ZO3
External IDs OMIM612689 MGI1351650 HomoloGene8458 GeneCards: TJP3 Gene
RNA expression pattern
PBB GE TJP3 213412 at tn.png
More reference expression data
Species Human Mouse
Entrez 27134 27375
Ensembl ENSG00000105289 ENSMUSG00000034917
UniProt O95049 E9QL54
RefSeq (mRNA) NM_001267560 NM_001282095
RefSeq (protein) NP_001254489 NP_001269024
Location (UCSC) Chr 19:
3.71 – 3.75 Mb
Chr 10:
81.27 – 81.29 Mb
PubMed search [1] [2]

Tight junction protein ZO-3 is a protein that in humans is encoded by the TJP3 gene.[1]


TJP3 has been shown to interact with Tight junction protein 1.[2]


  1. ^ "Entrez Gene: TJP3 tight junction protein 3 (zona occludens 3)". 
  2. ^ Wittchen, E S; Haskins J; Stevenson B R (Dec 1999). "Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3". J. Biol. Chem. (UNITED STATES) 274 (49): 35179–85. doi:10.1074/jbc.274.49.35179. ISSN 0021-9258. PMID 10575001. 

Further reading[edit]