TMSB10

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Thymosin beta 10
Identifiers
Symbols TMSB10 ; MIG12; TB10
External IDs OMIM188399 GeneCards: TMSB10 Gene
RNA expression pattern
PBB GE TMSB10 217733 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9168 n/a
Ensembl ENSG00000034510 n/a
UniProt P63313 n/a
RefSeq (mRNA) NM_021103 n/a
RefSeq (protein) NP_066926 n/a
Location (UCSC) Chr 2:
85.13 – 85.13 Mb
n/a
PubMed search [1] n/a

Thymosin beta-10 is a protein that in humans is encoded by the TMSB10 gene.[1][2][3] TMSB10 is a member of the beta-thymosin are a family of peptides.

TMSB10 plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).[citation needed]

References[edit]

  1. ^ McCreary V, Kartha S, Bell GI, Toback FG (Jun 1988). "Sequence of a human kidney cDNA clone encoding thymosin beta 10". Biochem Biophys Res Commun 152 (2): 862–6. doi:10.1016/S0006-291X(88)80118-9. PMID 3365256. 
  2. ^ Santelli G, Califano D, Chiappetta G, Vento MT, Bartoli PC, Zullo F, Trapasso F, Viglietto G, Fusco A (Oct 1999). "Thymosin beta-10 gene overexpression is a general event in human carcinogenesis". Am J Pathol 155 (3): 799–804. doi:10.1016/s0002-9440(10)65178-4. PMC 1866886. PMID 10487837. 
  3. ^ "Entrez Gene: TMSB10 thymosin, beta 10". 

Further reading[edit]