TOPORS

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Topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
Identifiers
Symbols TOPORS ; LUN; P53BP3; RP31; TP53BPL
External IDs OMIM609507 MGI2146189 HomoloGene4237 GeneCards: TOPORS Gene
RNA expression pattern
PBB GE TOPORS 204071 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10210 106021
Ensembl ENSG00000197579 ENSMUSG00000036822
UniProt Q9NS56 Q80Z37
RefSeq (mRNA) NM_001195622 NM_134097
RefSeq (protein) NP_001182551 NP_598858
Location (UCSC) Chr 9:
32.54 – 32.55 Mb
Chr 4:
40.26 – 40.27 Mb
PubMed search [1] [2]

E3 ubiquitin-protein ligase Topors is an enzyme that in humans is encoded by the TOPORS gene.[1][2][3][4]


References[edit]

  1. ^ Haluska P Jr, Saleem A, Rasheed Z, Ahmed F, Su EW, Liu LF, Rubin EH (Jul 1999). "Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein". Nucleic Acids Res 27 (12): 2538–44. doi:10.1093/nar/27.12.2538. PMC 148458. PMID 10352183. 
  2. ^ Rasheed ZA, Saleem A, Ravee Y, Pandolfi PP, Rubin EH (Jun 2002). "The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies". Exp Cell Res 277 (2): 152–60. doi:10.1006/excr.2002.5550. PMID 12083797. 
  3. ^ Chakarova CF, Papaioannou MG, Khanna H, Lopez I, Waseem N, Shah A, Theis T, Friedman J, Maubaret C, Bujakowska K, Veraitch B, Abd El-Aziz MM, Prescott de Q, Parapuram SK, Bickmore WA, Munro PM, Gal A, Hamel CP, Marigo V, Ponting CP, Wissinger B, Zrenner E, Matter K, Swaroop A, Koenekoop RK, Bhattacharya SS (Oct 2007). "Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy". Am J Hum Genet 81 (5): 1098–103. doi:10.1086/521953. PMC 2265653. PMID 17924349. 
  4. ^ "Entrez Gene: TOPORS topoisomerase I binding, arginine/serine-rich". 

Further reading[edit]

External links[edit]